Sandy (Kris Aquino) and Dale (Wendell Ramos) have just come home from abroad to get married, to the great joy of their relatives and friends. Shortly after, Sandy learns that her next door neighbor and friend Helen as well as Helen's husband and mother had all met tragic deaths. It is said that all these happened because Helen went against the taboo or superstition of getting married within a year of her father's death. This information dampens Sandy's spirit but her wedding pushes through. However, strange things start to happen. At first, these are attributed by Sandy and Joya (Dale's cousin gifted with a "third eye") to Helen in the haunted house but later Joya says that Sandy's marriage is cursed. This is because it defied a belief that siblings should not marry in the same year. But Sandy has no knowledge of a sibling in such circumstances. In her vision, Joya also sees another girl similarly cursed. This other girl is Diana (Claudine Barretto) who has just gotten married to Brian (Bernard Palanca) in a far away province. On their honeymoon, Brian dies but his body disappears. After Sandy's wedding, two cousins' bodies also disappear after an accident. Similar tragic and mysterious events happen almost simultaneously to Sandy and Diana though they are far apart and do not know each other. How explain these coincidences? How can tragedies be averted?